I thought I would miss the CD player in my car, but decided to take a chance on a Jensen head unit without one. I use a 128GB flash drive with the highest-res MP3s on it. The convenience and wide music selection far outweighes the difference in fidelity, I believe.
Still have a 6 CD changer and cassette player in my 2007 Acura TL so I keep that car mint at this time. The only thing bad is despite the car having Bluetooth, that doesn’t apply to the audio portion of the car.
Good advice above about getting a 2021 Acura TLX, that will be in my future.